Diazepam may produce physical dependence if used more frequently than recommended. Physical dependence is a state that develops as a result of physiological adaptation in response to repeated drug use, manifested by withdrawal signs and symptoms after abrupt discontinuation or a significant dose reduction of a drug. Inform patients that in some cases, patients taking benzodiazepines have developed a protracted withdrawal syndrome with withdrawal symptoms lasting weeks to more than 12 months (see WARNINGS and DRUG ABUSE AND DEPENDENCE). Instances are also reported within the high-dosage category of more serious developments such as seizures and psychotic reactions.
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Factors such as liver function, kidney function, age, and concurrent use of other medications can influence the metabolism and elimination of benzodiazepines from the body. Advise patients that there is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to diazepam tablets during pregnancy (see Precautions, heroin addiction Pregnancy). At Healthy Life Recovery, located in the heart of San Diego, CA, we understand the courage it takes to face addiction head-on.
General Health
- The benzodiazepine withdrawal process is impacted by factors such as the dosage, the duration of use, and whether the drug was stopped suddenly or tapered slowly.
- Professional withdrawal management programs can help you reduce your symptoms.
- Furthermore, psychosis is rare, but not unheard of, in those who taper their benzodiazepine slowly.
- It’s important to note that these are general estimates, and the actual detection window may vary based on individual factors and the sensitivity of the drug test used.
- These sensations return towards normal as withdrawal progresses, and some people are pleased with the new, seemingly extraordinary, clarity of their perceptions.
Dependence appears to occur in a similar way to how it does with other addictive drugs. Dopamine is a type of messenger that is partly responsible for how humans feel pleasure. Although many symptoms subside after the acute withdrawal phase, lingering side effects are possible. I hardly dare to mention smoking in view of present day attitudes to this unfortunate addiction, but for those who are smokers it is probably asking too much to attempt to stop smoking and withdraw benzodiazepines at the same time. Many people have found that giving up smoking is easier when they are off benzodiazepines, when the desire for nicotine may even wane somewhat.
Diazepam
The lower peak concentrations appear due to a slower rate of absorption, with the time abrupt withdrawal of benzodiazepines may result in: required to achieve peak concentrations on average minutes greater in the presence of antacids. Diazepam tablets are not recommended in the treatment of psychotic patients and should not be employed instead of appropriate treatment. In children 3-8 years old the mean half-life of diazepam has been reported to be 18 hours.
- There is absolutely no evidence that benzodiazepines cause permanent damage to the brain, nervous system or body.
- Many people have found that giving up smoking is easier when they are off benzodiazepines, when the desire for nicotine may even wane somewhat.
- In managing benzodiazepine overdosage, employ general supportive measures, including intravenous fluids and airway maintenance.
- The social and economic consequences of chronic benzodiazepine use are summarised in Table 3 (Chapter 1).
Other drugs
Recognizing these factors allows for a more informed and compassionate approach to managing withdrawal, emphasizing the importance of personalized care plans. By understanding and anticipating the challenges of benzodiazepine withdrawal, individuals and healthcare providers can work together to navigate this complex journey toward recovery. Understanding the complexities of benzodiazepine withdrawal is the first step toward managing it effectively. It requires a nuanced approach, considering the drug’s impact on the brain’s chemistry and the individual’s unique physiological and psychological makeup. With this knowledge, patients and healthcare providers can develop strategies to navigate withdrawal with greater safety and comfort. One of the critical aspects of understanding benzodiazepine withdrawal is recognizing the body’s adaptation to the drug’s effects.
How long does benzodiazepine withdrawal last?
Professional help is necessary to ensure safety and reduce discomfort during withdrawal from these drugs, as symptoms can be severe and, in some cases, life-threatening. Withdrawal from benzodiazepines is a result of the body’s reliance on the medication, which develops over time. Upon suddenly decreasing their dose or stopping them altogether, the nervous system reacts to the absence of benzos, causing a process of adjustment. Benzo withdrawals can be severe, and life threatening complications can occur.